2-pyridinecarboxamide, 4-methoxy- - Names and Identifiers
2-pyridinecarboxamide, 4-methoxy- - Physico-chemical Properties
Molecular Formula | C7H8N2O2
|
Molar Mass | 152.15 |
Density | 1.213g/cm3 |
Melting Point | 149.3°C |
Boling Point | 312.9°C at 760 mmHg |
Flash Point | 143.1°C |
Vapor Presure | 0.000513mmHg at 25°C |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.55 |
2-pyridinecarboxamide, 4-methoxy- - Risk and Safety
Risk Codes | R22 - Harmful if swallowed
R36 - Irritating to the eyes
|
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
|
Hazard Class | IRRITANT |
2-pyridinecarboxamide, 4-methoxy- - Introduction
It is an organic compound whose chemical formula is C7H8N2O2. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: It is a white to light yellow solid.
-Solubility: It is soluble in a variety of polar organic solvents, such as ethanol, dimethylformamide and dichloromethane.
-Melting point: Its melting point range is 110-115°C.
Use:
-chemical synthesis: it can be used as the starting material or intermediate of organic synthesis and participate in the synthesis reaction of various organic compounds.
-Drug research: This compound is widely used in the field of drug research. It can be used to prepare a variety of biologically active molecules, such as anti-cancer drugs, antibacterial drugs, etc.
Method:
The preparation of
can be carried out by the following route:
1. 4-methoxypyridine is reacted with benzyl chloride to give 4-methoxypyridinyl chloride.
2.4-methoxypyridinoyl chloride is then reacted with carbamate, and the target product is obtained by hydrolysis and crystal separation.
Safety Information:
-It has low toxicity, but as an organic compound, attention should still be paid to its safe use.
-Wear appropriate protective gloves, glasses and clothing to avoid contact with skin and eyes.
-During storage and handling, care should be taken to avoid ignition and high temperatures.
-If ingestion or irritant contact occurs, seek medical help immediately.
Please note that the above information is for reference only. If you need to use or handle the compound, please consult the relevant literature and safety information in detail, and take appropriate precautions according to the actual situation.
Last Update:2024-04-09 15:18:00